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Did you know?
Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
Did you know?
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The first oncogene was discovered in 1970 and was termed SRC (pronounced "SARK").
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By definition, when a medication is administered intravenously, its bioavailability is 100%.