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Author Question: Do the results from the TLC prove that the product is pure? ... (Read 38 times)

rayancarla1

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on: Aug 23, 2018
Do the results from the TLC prove that the product is pure? Explain.

Question 2

Why is the Opadry coating removed using ethanol instead of water?


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leahm14

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Reply #1 on: Aug 23, 2018
Answer to Question 1

No. You cannot use TLC to establish purity of a compound because there could be impurities that have the same Rf values as the compound. Impurities might also be present at different Rf's, but not visualized using standard techniques.

Answer to Question 2

The Opadry coating and sodium naproxen are both soluble in water. If water were used, some of the sodium naproxen would dissolve in the solution along with the Opadry. Separating these would be difficult. Sodium naproxen is not very soluble in ethanol and the Opadry coating is easy to remove using ethanol. Therefore, ethanol is the solvent of choice for removing the coating.


rayancarla1

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Reply 2 on: Aug 23, 2018
Thanks for the timely response, appreciate it

nyrave

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Reply 3 on: Yesterday
Wow, this really help

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