Which of the following compounds are primary (1) amines? ...

[maegan_martin]

Which of the following compounds are primary (1) amines?
   
 
   
  a.
  1 and 2
  b.
  1 and 3
  c.
  1, 2 and 3
  d.
  1, 2, 3 and 4

Question 2

Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry.
   
  Give the major product(s).
   
 

Question 3

Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry.
   
  Give major product(s):
   
 

Question 4

Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry.
   
   
 

Question 5

Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry.
   
  Give major product(s):
   
 

Question 6

Instructions: Give the major organic product(s) of each of the following reaction or sequence of reactions. Show all relevant stereochemistry.
   
  Give major product(s):
   
 

Question 7

Rank the following compounds in order of increasing basicity. Label the least basic compound 1 and the most basic compound 4. Place the number corresponding to the compound's rank in the blank below the compound.
   
 

Question 8

In the following series of compounds, which is the most basic and the least basic? Explain your choices.
   
 

Question 9

Circle any of the following that would be classified as a heterocyclic amine.
   
 

Question 10

Instructions: Consider the reaction below to answer the following question(s).
   
  Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H₂/Ni.
   
 
  Refer to instructions. Although the yield of methamphetamine is good, some unreacted phenyl-2-propanone remains after the reaction is complete. Describe how methamphetamine can be separated from phenyl-2-propanone.

Question 11

Instructions: Consider the reaction below to answer the following question(s).
   
  Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H₂/Ni.
   
 
  Refer to instructions. The synthesis of methamphetamine by reaction of 2-phenyl-2 propanone with methylamine in the presence of H₂/Ni is referred to as:
   
  a.
  reductive nitrogenation
  b.
  reactive nitrogenation
  c.
  reductive amination
  d.
  reactive amination

Question 12

Instructions: Consider the reaction below to answer the following question(s).
   
  Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H₂/Ni.
   
 
  Refer to instructions. Intermediate A is an example of:
  a.
  an imine
  b.
  an enamine
  c.
  an iminium ion
  d.
  an imide

Question 13

Instructions: Consider the reaction below to answer the following question(s).
   
  Methamphetamine can be synthesized by reacting phenyl-2-propanone with methylamine in the presence of H₂/Ni.
   
 
  Refer to instructions. Identify the nucleophile in the initial reaction of phenyl-2-propanone to yield intermediate A and classify the type of reaction that produces the final product from A.

Question 14

Instructions: Based on the following structures, name the compound.
  Name:
   
 

Question 15

Instructions: Based on the following structures, name the compound.
  Name:
   
 

Question 16

Instructions: Based on the following structures, name the compound.
  Name:
   
 

Question 17

Instructions: Based on the following structures, name the compound.
  Name:
   
 

Question 18

Instructions: Draw structures corresponding to each of the IUPAC names given in the following question(s).
  Draw:
   
   N,N-dimethylcyclopentylamine

Question 19

Instructions: Draw structures corresponding to each of the IUPAC names given in the following question(s).
  Draw:
   
   hexane-1,6-diamine

[tdewitt]

Answer to Question 1

c

Answer to Question 2



Answer to Question 3



Answer to Question 4



Answer to Question 5



Answer to Question 6



Answer to Question 7



Answer to Question 8

ANS: CH₃CH₂CH₂NH₂

Strongest base because it is the only aliphatic amine.



Weakest based because it is an amide not an amine and is not considered basic.

Answer to Question 9



Answer to Question 10

Dissolve the reaction mixture containing the ketone and amine in ether and extract with aqueous HCl. The basic amine will dissolve in the aqueous layer as its hydrochloric salt. The neutral ketone will remain in the ether layer. Separate the two layers and neutralize the aqueous layer with NaOH. Extract the neutralized layer with ether. The purified amine will dissolve in the ether.

Answer to Question 11

c

Answer to Question 12

a

Answer to Question 13

ANS: The nucleophile is methylamine and the final (second) reaction is a reduction.

Answer to Question 14

ANS: 2,4-hexanediamine

Answer to Question 15

ANS: N-ethylaniline

Answer to Question 16

ANS: methyl-2-aminobutanoate

Answer to Question 17

ANS: p-methoxyaniline or 4-methoxyaniline

Answer to Question 18



Answer to Question 19

ANS: H₂NCH₂CH₂ CH₂CH₂CH₂CH₂NH₂

[maegan_martin]

Thank you!

[tdewitt]

Always glad to help...