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Author Question: Suppose that the formation of a dipeptide is endergonic by +14.7 kJ/mol. If this reaction is coupled ... (Read 165 times)

bcretired

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on: Aug 23, 2018
Suppose that the formation of a dipeptide is endergonic by +14.7 kJ/mol. If this reaction is coupled with the hydrolysis of ATP, will the net reaction be spontaneous or nonspontaneous? Explain your answer.

Question 2

Many biological reactions are endergonic. Explain how it is possible that these reactions occur spontaneously.


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14vl19

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Reply #1 on: Aug 23, 2018
Answer to Question 1

The net reaction will be spontaneous since the Gnet value is 15.8 kJ/mol. This is based on coupling the endergonic reaction with a G of +14.7 kJ/mol with the exergonic hydrolysis of ATP with a G value of 30.5 kJ/mol. Gnet = 30.5 kJ/mol +14.7 kJ/mol = 15.8 kJ/mol.

Answer to Question 2

Endergonic reactions such as the conversion of glucose to glucose-6-phosphate are coupled with highly exergonic reactions such as the hydrolysis of ATP to ADP such that the overall reaction is exergonic and therefore spontaneous.


bcretired

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Reply 2 on: Aug 23, 2018
Wow, this really help

juliaf

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Reply 3 on: Yesterday
YES! Correct, THANKS for helping me on my review

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