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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Approximately 500,000 babies are born each year in the United States to teenage mothers.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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The longest a person has survived after a heart transplant is 24 years.