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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
There can actually be a 25-hour time difference between certain locations in the world. The International Date Line passes between the islands of Samoa and American Samoa. It is not a straight line, but "zig-zags" around various island chains. Therefore, Samoa and nearby islands have one date, while American Samoa and nearby islands are one day behind. Daylight saving time is used in some islands, but not in others—further shifting the hours out of sync with natural time.
When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
According to the National Institute of Environmental Health Sciences, lung disease is the third leading killer in the United States, responsible for one in seven deaths. It is the leading cause of death among infants under the age of one year.