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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
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Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.
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To prove that stomach ulcers were caused by bacteria and not by stress, a researcher consumed an entire laboratory beaker full of bacterial culture. After this, he did indeed develop stomach ulcers, and won the Nobel Prize for his discovery.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.