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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
There are approximately 3 million unintended pregnancies in the United States each year.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
More than 4.4billion prescriptions were dispensed within the United States in 2016.