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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The FDA recognizes 118 routes of administration.
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There are more nerve cells in one human brain than there are stars in the Milky Way.
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Approximately 500,000 babies are born each year in the United States to teenage mothers.
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Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.