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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Nearly 31 million adults in America have a total cholesterol level that is more than 240 mg per dL.
The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.