This topic contains a solution. Click here to go to the answer

Author Question: The effective dose 50 (ED50) value for Drug A is 2.0 mg/kg while its lethal dose 50 (LD50) value is ... (Read 149 times)

jeatrice

  • Hero Member
  • *****
  • Posts: 543
The effective dose 50 (ED50) value for Drug A is 2.0 mg/kg while its lethal dose 50 (LD50) value is 8 mg/kg. Which of the following is true of Drug A?
 
  A) Drug A is ineffective for its intended purpose.
  B) Drug A has a therapeutic index of 4.0.
  C) Drug A is safe for use in humans.
  D) The therapeutic index of Drug A is 0.25.
  E) The therapeutic index of Drug A is 25.

Question 2

Repeated administration of a constant drug dose typically produces ________, which is defined as a(n) ________ effect of the drug.
 
  A) dynamic capacity; increased
  B) sensitization; reduced
  C) behavioral inactivation; increased
  D) tolerance; reduced
  E) homeostasis; constant



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

yotaSR5

  • Sr. Member
  • ****
  • Posts: 331
Answer to Question 1

Answer: B
Rationale: Assuming that Drug A has an ED50 value of 2.0 mg/kg while its lethal dose 50 (LD50) value is 8 mg/kg, Drug A has a therapeutic index of 4.0.

Answer to Question 2

Answer: D
Rationale: Repeated administration of a constant drug dose typically produces tolerance, which is defined as a reduced effect of the drug over time.





 

Did you know?

Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.

Did you know?

During pregnancy, a woman is more likely to experience bleeding gums and nosebleeds caused by hormonal changes that increase blood flow to the mouth and nose.

Did you know?

Patients who have undergone chemotherapy for the treatment of cancer often complain of a lack of mental focus; memory loss; and a general diminution in abilities such as multitasking, attention span, and general mental agility.

Did you know?

The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.

Did you know?

Normal urine is sterile. It contains fluids, salts, and waste products. It is free of bacteria, viruses, and fungi.

For a complete list of videos, visit our video library