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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
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The longest a person has survived after a heart transplant is 24 years.
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Everyone has one nostril that is larger than the other.
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According to the Migraine Research Foundation, migraines are the third most prevalent illness in the world. Women are most affected (18%), followed by children of both sexes (10%), and men (6%).