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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.

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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.

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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.

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Essential fatty acids have been shown to be effective against ulcers, asthma, dental cavities, and skin disorders such as acne.

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A seasonal flu vaccine is the best way to reduce the chances you will get seasonal influenza and spread it to others.

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