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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.

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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.

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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.

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The term bacteria was devised in the 19th century by German biologist Ferdinand Cohn. He based it on the Greek word "bakterion" meaning a small rod or staff. Cohn is considered to be the father of modern bacteriology.

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Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.

Urinary System Urinary System
Position of the urinary organs. Position of the urinary organs.
Cystostomy. An artificial opening is made through the urinary bladder wall during this procedure. As Cystostomy. An artificial opening is made through the urinary bladder wall during this procedure. As
Urinary system. Urinary system.
(B) Urine collection cup; (C) 24-hour urine container. (B) Urine collection cup; (C) 24-hour urine container.
17th Century Physician Examining a Urine Specimen 17th Century Physician Examining a Urine Specimen
Video: Aneurysm

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