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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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People about to have surgery must tell their health care providers about all supplements they take.
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Many of the drugs used by neuroscientists are derived from toxic plants and venomous animals (such as snakes, spiders, snails, and puffer fish).
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In 1864, the first barbiturate (barbituric acid) was synthesized.