A drug inducing its own metabolism and subsequently having a lowered concentration and need to increase the dose to maintain a previously achieved response is an example of
a. Pharmacodynamically achieved tolerance.
b. Pharmacokinetically achieved tolerance.
c. Pharmacodynamically achieved dependence.
d. Pharmacokinetically achieved tolerance.
Question 2
The development of drug tolerance appears to be associated with all of the following but which one?
a. Altered gene expression induced by a drug.
b. The occurrence of a withdrawal syndrome from the abrupt
discontinuation of a drug.
c. Receptor down regulation.
d. Increased metabolism of a drug resulting on lowered drug
concentrations.
Multiple-dose drug administration: drug A and drug B are administered every 12 hours; drug B reaches
Calcium metabolism in osteoporosis: (a) bone deposition equals bone resorption; (b) bone resorption ...
First-pass metabolism (biotransformation). Absorption of an orally administered drug.
Dietary polysaccharides Metabolism
Blood Alcohol Concentration in men and women
Male to Female Sex Ratio at Birth vs. PCB Concentration in Maternal Serum