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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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Cytomegalovirus affects nearly the same amount of newborns every year as Down syndrome.