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Author Question: When drugs with sedative-hypnotic properties are administered chronically, what is the general ... (Read 41 times)

cookcarl

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on: Jun 22, 2018
When drugs with sedative-hypnotic properties are administered chronically, what is the general effect on the P450 enzymes of the liver?
 
  What will be an ideal response?

Question 2

The effects of a particular dose of a drug may differ significantly in young adults and elderly people, even if the dose is administered on a mg/kg basis. Give two reasons why this may occur.
 
  What will be an ideal response?


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stanleka1

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Reply #1 on: Jun 22, 2018
Answer to Question 1

The rate of synthesis and levels of these enzymes will increase over time

Answer to Question 2

Younger adults have more P450 enzymes and more efficient kidney function; thus, metabolization and excretion is more efficient than in elderly people.


cookcarl

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Reply 2 on: Jun 22, 2018
Great answer, keep it coming :)

juliaf

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Reply 3 on: Yesterday
Excellent

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