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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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During the twentieth century, a variant of the metric system was used in Russia and France in which the base unit of mass was the tonne. Instead of kilograms, this system used millitonnes (mt).
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Illicit drug use costs the United States approximately $181 billion every year.