Curare is a poisonous plant extract. Curare molecules have a chemical structure like the neurotransmitter ACh. Curare can bind to the ACh receptor site on the chemically gated ion channels in the motor end plate. Even though curare will bind to the receptor site it will not open the ion channel and no ions will pass through. What do you think the symptoms of curare poisoning would look like?
◦ Smooth muscles will become stimulated causing quick movement of nutrients through the digestive system.
◦ Muscles will respond too quickly and cause a severe tremor.
◦ Curare will only affect cardiac muscle, causing fibrillations of the heart.
◦ Curare will only affect muscles with ACh receptors, paralyzing them.
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