The relatively long half-life of lipid soluble hormones (steroid hormones) compared to water soluble hormones is due in part to the way that these hormones are passed into the filtrate from the glomerular capillaries. From the list below select the best explanation for why lipid soluble (steroid) hormones have a relatively long half-life.
◦ The large size of the steroid hormones prevents them from passing through the filtration membrane.
◦ Steroid hormones are absorbed by target cells before they can reach the kidneys.
◦ Steroid hormones travel in the plasma on large transport proteins that cannon pass through the filtration membrane.
◦ The relatively small size of steroid hormones allows them to easily pass back into the peritubular capillaries if released into the filtrate.
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