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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The horizontal fraction bar was introduced by the Arabs.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.