Question 1
Which chemical mediator derived from mast cells retracts endothelial cells to increase vascular permeability and to cause leukocyte adhesion to endothelial cells?
◦ Chemokines
◦ Prostaglandin E
◦ Platelet-activating factor
◦ Bradykinin
Question 2
What is the inflammatory effect of nitric oxide (NO)?
◦ Increases capillary permeability, and causes pain
◦ Increases neutrophil chemotaxis and platelet aggregation
◦ Causes smooth muscle contraction and fever
◦ Decreases mast cell function, and decreases platelet aggregation