Question 1
By what process do cancer cells multiply in the absence of external growth signals?
◦ Proto-oncogene
◦ Autocrine stimulation
◦ Reliance on caretaker genes
◦ Pleomorphology
Question 2
What is the role of caretaker genes?
◦ Maintenance of genomic integrity
◦ Proliferation of cancer cells
◦ Secretion of growth factors
◦ Restoration of normal tissue structure