In osteomyelitis, bacteria gain access to the subperiosteal space in the metaphysis. What factor makes this route the easiest for bacteria to gain access to this area?
◦ Cortex of the bone in this area is porous or mazelike.
◦ Blood supply to the metaphysis is easily compromised.
◦ Macrophages and lymphocytes have limited access to the subperiosteal space.
◦ Bacteria usually spread down the medullary cavity of the bone.