Hereditary anemia known as sickle cell disease (SCD) results from inheritance of a variant form of β-globin protein (βS), rather than the wild-type β-globin protein (βA). Which of the following did Linus Pauling find following gel electrophoresis of hemoglobin protein from individuals with the following three genotypes: βAβA, βAβS, or βSβS?
◦ the lane containing the hemoglobin from the heterozygote (βAβS) individual had two protein bands with differing electrophoretic mobility
◦ the lane containing the hemoglobin from the homozygous (βAβA) individual had two protein bands with differing electrophoretic mobility
◦ the lane containing the hemoglobin from the homozygous (βSβS) individual with SCD had two protein bands
◦ all three lanes had the same two protein bands with the same electrophoretic mobility
◦ all three lanes had just one protein band with the same electrophoretic mobility
Cell Division
Inheritance of the sickle cell trait and sickle cell anemia.
Stem cell research may cure diabetes, but lacks funding
Cell kill and chemotherapy.
Parkinson’s disease
An antigen-presenting dendritic cell (blue) interacting with a T cell (yellow)