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Author Question: Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its ... (Read 17 times)

sbegs

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on: Feb 17, 2022

Question 1

Indicate which pattern of arrow pushing it is involved in the reaction step shown.



◦ proton transfer
◦ loss of leaving group
◦ nucleophilic attack
◦ rearrangement

Question 2

Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below.  Which two patterns of arrow pushing are seen in this reaction?

Organic Chemistry ¦ Klein ¦ 4th Edition
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Marked as best answer by sbegs on Feb 17, 2022

H.cope00

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Reply #1 on: Feb 17, 2022
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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sbegs

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Reply 2 on: Feb 17, 2022
Great answer, keep it coming :)

komodo7

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Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

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