Question 1
Regulatory proteins are most likely to bind at:
◦ the central part of DNA in the nucleosome.
◦ the core histones themselves.
◦ any DNA associated with nucleosomes.
◦ the linker sequences between nucleosomes.
◦ the H1 linker histone.
Question 2
Suppose an insulator that is located between an enhancer and a gene's promoter were to be deleted by mutation. What would be the effect of the mutation on the gene's expression?
◦ There would be no effect of the mutation.
◦ The gene would never be expressed.
◦ Gene expression levels would decrease.
◦ Gene expression levels would increase.
◦ The gene would be expressed constitutively.