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Author Question: One of the human leukemias, called CML (chronic myelogenous leukemia), is associ (Read 818 times)

aero

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on: Jun 29, 2013
One of the human leukemias, called CML (chronic myelogenous leukemia), is associated with a chromosomal translocation between chromosomes 9 and 22 in somatic cells of bone marrow. Which of the following allows CML to provide further evidence of this multistep nature of cancer?
A) CML usually occurs in more elderly persons (late age of onset).
B) The resulting chromosome 22 is abnormally short; it is then known as the Philadelphia chromosome.
C) The translocation requires breaks in both chromosomes 9 and 22, followed by fusion between the reciprocal pieces.
D) CML involves a proto-oncogene known as abl.
E) CML can usually be treated by chemotherapy.


Hawke

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Reply #1 on: Jul 1, 2013
I'd go with C. It makes sense.


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aero

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Reply #2 on: Jul 23, 2013
Thanks Hawke :D


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