One of the human leukemias, called CML (chronic myelogenous leukemia), is associated with a chromosomal translocation between chromosomes 9 and 22 in somatic cells of bone marrow. Which of the following allows CML to provide further evidence of this multistep nature of cancer?
A) CML usually occurs in more elderly persons (late age of onset).
B) The resulting chromosome 22 is abnormally short; it is then known as the Philadelphia chromosome.
C) The translocation requires breaks in both chromosomes 9 and 22, followed by fusion between the reciprocal pieces.
D) CML involves a proto-oncogene known as abl.
E) CML can usually be treated by chemotherapy.
Diffusion spectrum MR image of human brain
human anatomy
Human skull
Nine pulse sites on the human body.
The Human Tongue and Taste Buds
Human chromosomes as seen at metaphase of mitosis in the scanning electron microscope. The replicate