A researcher has used in vitro mutagenesis to mutate a cloned gene and then has reinserted this into a cell. In order to have the mutated sequence disable the function of the gene, what must then occur?
A) recombination resulting in replacement of the wild type with the mutated gene
B) use of a microarray to verify continued expression of the original gene
C) replication of the cloned gene using a bacterial plasmid
D) transcription of the cloned gene using a BAC
E) attachment of the mutated gene to an existing mRNA to be translated
Single-gene inheritance tracked at the DNA level
Relationship between the number of CAG repeats in a gene and the age of onset of Huntington disease.
Gene Duplication
Gene therapy can prevent progression of metachromatic leukodystrophy
Alternative splicing of the Dscam gene mRNA
Evolution of the vertebrate SR gene family