A researcher has used in vitro mutagenesis to mutate a cloned gene and then has reinserted this into a cell. In order to have the mutated sequence disable the function of the gene, what must then occur?
A) recombination resulting in replacement of the wild type with the mutated gene
B) use of a microarray to verify continued expression of the original gene
C) replication of the cloned gene using a bacterial plasmid
D) transcription of the cloned gene using a BAC
E) attachment of the mutated gene to an existing mRNA to be translated
A missense mutation that converts the normal ras gene into an oncogene.
The exponential amplification of the gene in PCR.
Actions of mutM, mutT, and mutY gene products in countering the mutagenic effect of 8-oxoguanine -oG
Dolly, a Finn Dorset sheep cloned from the genetic material o
The first successful gene therapy trial
A gene map for chromosome 12 from the NCBI database Map Viewer