Dietary fats and minerals can foster or inhibit drug absorption. ...

[segrsyd]

Dietary fats and minerals can foster or inhibit drug absorption. Likewise, some drugs can change the availability of nutrients. This mechanism is classified as:
 
  1. Alteration in chelation.
   2. Alteration in bioavailability.
   3. Alteration in metabolism.
   4. Alteration in excretion.

Question 2

The nurse has been caring for a client in ICU who is receiving enteral nutrition (EN) via continuous drip method. As per the orders, the nurse is assessing gastric residuals.
 
  The nurse is aware that the feeding should be withheld and the client tolerance reassessed if the residual measures which of the following? A) Greater than 300 mL C) Greater than 500 mL
  B) Greater than 400 mL D) Greater than 600 mL

[Jane]

Answer to Question 1

2
Rationale: Certain components of food such as fats and minerals can change the bioavailability of drugs, and some drugs can change the availability of nutrients, by fostering or interfering with absorption. Chelation is a type of binding that occurs between a metal ion and another molecule which results in reduced bioavailability. Alterations in metabolism occur after absorption is complete and the substances are in route to the tissues. Alteration in excretion refers to elimination of the byproducts of metabolism.

Answer to Question 2

C
Feedback:
Gastric residuals should be measured every 4 to 6 hours. If the volume of gastric residual exceeds 500 mL, the feeding should be held and client tolerance reassessed.

[segrsyd]

TYSM

Thanks for the timely response, appreciate it