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Author Question: What is the pathophysiologic process responsible for the autoimmune disorder of hemolytic-uremic ... (Read 71 times)

WhattoUnderstand

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on: Aug 28, 2021

Question 1

In immunoglobulin G (IgG) nephropathies such as glomerulonephritis, IgG is deposited in which location?

◦ Juxtamedullary nephrons
◦ Glomerulus basement membranes
◦ Mesangium of the glomerular capillaries
◦ Parietal epithelium

Question 2

What is the pathophysiologic process responsible for the autoimmune disorder of hemolytic-uremic syndrome (HUS)?

◦ Immunoglobulin A (IgA) coats erythrocytes that are destroyed by the spleen, and remnants are excreted through the kidneys.
◦ Verotoxin from Escherichia coli is absorbed from the intestines and damages erythrocytes and endothelial cells.
◦ Endotoxins from E. coli block the erythropoietin produced by the kidneys, which reduces the number of erythrocytes produced by the bone marrow.
◦ Failure of the nephron to filter urea increases the blood urea nitrogen, which binds to erythrocytes that are subsequently destroyed by the spleen.
Pathophysiology: The Biologic Basis of Disease in Adults and Children ¦ McCance, Huether ¦ 8th Edition
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Marked as best answer by WhattoUnderstand on Aug 28, 2021

C.mcnichol98

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Reply #1 on: Aug 28, 2021
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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WhattoUnderstand

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Reply 2 on: Aug 28, 2021
Great answer, keep it coming :)

pratush dev

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Reply 3 on: Yesterday
Wow, this really help

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