This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: DNA helicase inhibitors are well studied as potential drug targets. What would you expect to seeif ... (Read 16 times)

CORALGRILL2014

  • Hero Member
  • *****
  • Posts: 525
on: Jan 12, 2022
DNA helicase inhibitors are well studied as potential drug targets. What would you expect to see 
if DNA helicase activity is inhibited?
◦ The replisome complex would not assemble on the oriC region.
◦ The DNA cannot bend, so hydrogen bonds in the 13-mer region of oriC remain intact.
◦ Helicase catalyzes ATP hydrolysis and DNA strands separation, so the helix cannot be unwound and strands will not separate.
◦ Helicase carries the SSB protein to the open region of DNA, so hydrolysis and strand separation will not occur.
◦ Helicase prevents reannealing of the separated strands, so strands would quickly reanneal and DNA replication cannot proceed.
Genetic Analysis: An Integrated Approach ¦ Sanders, Bowman ¦ 3rd Edition
Buy Test-Bank


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by CORALGRILL2014 on Jan 12, 2022

ansleighelindsey

  • Sr. Member
  • ****
  • Posts: 364
Reply #1 on: Jan 12, 2022
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
Answer Preview
Only 45% of students answer this correctly


CORALGRILL2014

  • Member
  • Posts: 525
Reply 2 on: Jan 12, 2022
:D TYSM

meow1234

  • Member
  • Posts: 333
Reply 3 on: Yesterday
Wow, this really help

« previous next »
 

Did you know?

The newest statin drug, rosuvastatin, has been called a superstatin because it appears to reduce LDL cholesterol to a greater degree than the other approved statin drugs.

Did you know?

Approximately 500,000 babies are born each year in the United States to teenage mothers.

Did you know?

Bacteria have flourished on the earth for over three billion years. They were the first life forms on the planet.

Did you know?

The highest suicide rate in the United States is among people ages 65 years and older. Almost 15% of people in this age group commit suicide every year.

Did you know?

Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.

Drug Interaction with Receptor Site Drug Interaction with Receptor Site
Membrane potential of a cell freely permeable to sodium only. Membrane potential of a cell freely permeable to sodium only.
Isozymes of Cytochrome P450: Selected Substrates, Inducers, and Inhibitors Isozymes of Cytochrome P450: Selected Substrates, Inducers, and Inhibitors
Food and Drug Administration (FDA) Pregnancy Categories Food and Drug Administration (FDA) Pregnancy Categories
The Dose-Effect Relationship, Showing (A) Drug Potency and (B) Drug Efficacy (Or Effectiveness) The Dose-Effect Relationship, Showing (A) Drug Potency and (B) Drug Efficacy (Or Effectiveness)
Estimating Potential Blood Volume Loss (Part 1) Estimating Potential Blood Volume Loss (Part 1)
Video: Vasectomy

For a complete list of videos, visit our video library