Which of the following alkylating agents can cross the ...

[2125004343]

Which of the following alkylating agents can cross the blood-brain barrier? Select all that apply.
 
  A) Cisplatin (Platinol-AQ)
  B) Melphalan (Alkeran)
  C) Carmustine (BiCNU)
  D) Streptozocin (Zanosar)
  E) Mechlorethamine (Mustargen)

Question 2

After reviewing information about colony-stimulating factors, a group of nursing students demonstrate understanding of the information when they identify which of the following as true about filgrastim (Neupogen)? Select all that apply.
 
  A) Is a glycoprotein
  B) Promotes proliferation of leukocytes
  C) Stimulates differentiation of erythrocytes
  D) Stimulates maturation of megakaryocytes
  E) Is used to treat chemotherapy-induced neutropenia

[Galvarado142]

Answer to Question 1

Ans: C, D
Feedback:
Nitrosoureas, like carmustine (BiCNU) and streptozocin (Zanosar), are alkylating agents that can cross the blood-brain barrier.

Answer to Question 2

Ans: A, B, E
Feedback:
Colony-stimulating factors such as filgrastim (Neupogen) are glycoproteins used to stimulate proliferation, differentiation, and maturation of leukocytes. They are used to treat chemotherapy-induced neutropenia.

[2125004343]

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[xthemafja]

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