Where are malignant plasma cells found in plasma cell myeloma? ...

[mckennatimberlake]

Where are malignant plasma cells found in plasma cell myeloma?
 
  a. Bone marrow and sometimes in the peripheral blood
  b. Lymph nodes and liver
  c. Spleen and liver
  d. Bone marrow and lymph nodes

Question 2

A middle-aged man has a white blood cell (WBC) count of 80  109/L with 90 lymphocytes and many smudge cells. Which of the following is most likely?
 
  a. Chronic lymphocytic leukemia
  b. Hairy cell leukemia
  c. T-cell lymphoma
  d. Szary syndrome

[billybob123]

Answer to Question 1

ANS: A
The malignant plasma cells in plasma cell myeloma are found in the bone marrow. Occasionally, but not often, they circulate in the peripheral blood. When they exceed 20 in the peripheral blood, or the plasma cell count exceeds 2.0  109/L, it is called plasma cell leukemia.

Answer to Question 2

ANS: A
Chronic lymphocytic leukemia is characterized by the accumulation of small lymphoid cells in the peripheral blood, with a lymphocytosis greater than10  109/L. Smudge cells, representing disintegrated lymphoid cells, are also present. They are of diagnostic significance.

[mckennatimberlake]

TYSM

[nanny]

Excellent