Although found in most chronic myeloproliferative disorders, ...

[mspears3]

Although found in most chronic myeloproliferative disorders, increased fibrosis detected by the silver techniques and trichrome stain is the key feature of:
 
  a. Secondary polycythemia
  b. Chronic myelogenous leukemia
  c. Essential thrombocythemia
  d. Primary myelofibrosis

Question 2

What clinical feature is more often associated with essential thrombocytosis than with the other chronic myeloproliferative disorders?
 
  a. Splenomegaly
  b. Bleeding and thrombosis
  c. Fatigue
  d. Infections

[lin77x]

Answer to Question 1

ANS: D
This is a key feature of primary myelofibrosis.

Answer to Question 2

ANS: B
Bleeding and thromboembolic complications are characteristic of essential thrombocytosis. Patients with polycythemia vera who are treated only with phlebotomy are at increased risk for bleeding and thrombosis, but it is otherwise not characteristic of polycythemia vera. Splenomegaly is seen in all the myeloproliferative disorders, as are fatigue and infections.

[mspears3]

Great answer, keep it coming

[tanna.moeller]

Thanks for the timely response, appreciate it