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Author Question: What finding is present in all types of a-thalassemias? a. Hemoglobin H (Hb H) inclusions seen ... (Read 55 times)

roselinechinyere27m

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on: Jun 25, 2018
What finding is present in all types of a-thalassemias?
 
  a. Hemoglobin H (Hb H) inclusions seen with Brilliant cresyl blue
  b. Anemia
  c. Microcytic hypochromic red cells
  d. Barts hemoglobin present at birth

Question 2

Which of the following is true of patients with Hb H disease?
 
  a. Have a severe anemia
  b. Have three missing genes for a chain production
  c. Have excess unpaired b chains present
  d. Are of Northern European ethnicity


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okolip

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: D
Barts (g4) hemoglobin is present at birth in all forms of a-thalassemia. Hb H inclusions, anemia, and microcytic red cells are not found in all forms.

Answer to Question 2

ANS: B
Hb H disease occurs when three genes are missing for a globin chain synthesis and an excess of b chains (b4), which is named Hb H, is present and easily detectable. A mild to moderate anemia is present. These individuals are primarily of Asian ethnicity.


roselinechinyere27m

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Reply #2 on: Jun 25, 2018
Thank you :)


okolip

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Reply #3 on: Jun 25, 2018
Happy to help you


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