Ringed sideroblasts are seen in: a. Inherited sideroblastic ...

[EY67]

Ringed sideroblasts are seen in:
 
  a. Inherited sideroblastic anemia
  b. Acquired hemochromatosis
  c. Iron deficiency anemia
  d. ACI

Question 2

Which of the following is true of stage 3 iron deficiency?
 
  a. Serum transferrin receptors are decreased.
  b. FEP is increased.
  c. The number of sideroblasts is normal.
  d. The red cell count is increased, whereas the hematocrit is decreased.

[jonathanballen97]

Answer to Question 1

ANS: A
Ringed sideroblasts are seen in the inherited forms of sideroblastic anemia but not in any of the other conditions listed.

Answer to Question 2

ANS: B
FEP increases because not enough adequate iron is available to insert into protoporphyrin IX. Transferrin receptors on the membrane of developing cells increase as the cells try to capture as much iron as possible (from what is bound to transferrin); these receptors are shed into plasma so that they increase (actually happens in stage 2). The number of sideroblasts will essentially be absent, because no excess iron is going to the developing red cells. The red cell count, as well as the hematocrit, is decreased.