Author Question: The A1c modified component of Hb A is increased in what condition? a. Sickle cell anemia b. ... (Read 211 times)

sarasara

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The A1c modified component of Hb A is increased in what condition?
 
  a. Sickle cell anemia
  b. Thalassemia
  c. Disorders of heme
  d. Uncontrolled diabetes mellitus

Question 2

Why does Hb F have a higher oxygen affinity than adult hemoglobin?
 
  a. Fetal blood has a higher pH than adult blood.
  b. Fetal blood has a higher hematocrit than adult blood.
  c. Body temperature is lower in fetus.
  d. It is necessary to extract oxygen from the maternal blood supply.



fffftttt

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Answer to Question 1

ANS: D
Hemoglobin is a posttranslational modification of hemoglobin in which the hemoglobin molecule is glycated. Its concentration is increased when diabetes is uncontrolled.

Answer to Question 2

ANS: D
The fetus has a need for oxygen. In order for the fetus to extract oxygen from the mother's blood (cord blood), its affinity for hemoglobin must be higher than that of the mother.



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