A 57-year-old male was admitted to the hospital with suspicion of AML. Preliminary CBC results show a high WBC count with 47 blasts present. Cytochemical staining shows negative reactions with MPO, SBB, and NSE. Platelet peroxidase staining was positive.
Immunophenotyping was also ordered.
Predict the results of the immunophenotyping panel based on the information already given.
a. Positive reactions with CD13, CD33, and CD34
b. Positive reactions with CD41, CD42, and CD61
c. Positive reactions with HLA-DR and CD13
d. Positive reactions with CD11b and CD14
Question 2
A patient presents with bleeding and is found to be in DIC. The peripheral smear contains hypergranular promyelocytes. The white count is slightly elevated. The bone marrow contains cells with multiple Auer rods with a clear blue cytoplasm.
a. AML with 11q23 abnormalities
b. AML with t(15;17) q22;q12)
c. Microgranular APL variant
d. AML with multilineage dysplasia
