A client is starting hormonal therapy with tamoxifen (Nolvadex) ...

[nevelica]

A client is starting hormonal therapy with tamoxifen (Nolvadex) to lower the risk for breast cancer. What information needs to be explained by the nurse regarding the action of this drug?
 
  a. It blocks the release of luteinizing hormone.
  b. It interferes with cancer cell division.
  c. It selectively blocks estrogen in the breast.
  d. It inhibits DNA synthesis in rapidly dividing cells.

Question 2

During dressing changes, the nurse assesses a client who has had breast reconstruction. Which finding would cause the nurse to take immediate action?
 
  a. Slightly reddened incisional area
  b. Blood pressure of 128/75 mm Hg
  c. Temperature of 99  F (37.2  C)
  d. Dusky color of the flap

[amit]

Answer to Question 1

ANS: C
Tamoxifen (Nolvadex) reduces the estrogen available to breast tumors to stop or prevent growth. This drug does not block the release of luteinizing hormone to prevent the ovaries from producing estrogen; leuprolide (Lupron) does this. Chemotherapy agents such as ixabepilone (Ixempra) interfere with cancer cell division, and doxorubicin (Adriamycin) inhibits DNA synthesis in susceptible cells.

Answer to Question 2

ANS: D
A dusky color of the breast flap could indicate poor tissue perfusion and a decreased capillary refill. The nurse should notify the surgeon to preserve the tissue. It is normal to have a slightly reddened incision as the skin heals. The blood pressure is within normal limits and the temperature is slightly elevated but should be monitored.

[nevelica]

Excellent

[vickyvicksss]

Thanks for the timely response, appreciate it