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An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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The FDA recognizes 118 routes of administration.