This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Which of the following are true regarding glucocorticoids? 1. They work through activation of ... (Read 18 times)

jazziefee

  • Hero Member
  • *****
  • Posts: 505
on: Jul 16, 2018
Which of the following are true regarding glucocorticoids?
 
  1. They work through activation of intracellular receptors.
  2. Relief is immediate.
  3. Daily compliance is essential to controlling inflammation in asthma.
  4. They work in a similar fashion to adrenergic bronchodilators.
  a. 1 and 3 only
  b. 1, 3, and 4 only
  c. 2, 3, and 4 only
  d. 1, 2, 3, and 4

Question 2

Which of the following inhaled corticosteroids is a prodrug?
 
  a. Ciclesonide
  b. Flunisolide
  c. Budesonide
  d. Triamcinolone


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

raenoj

  • Sr. Member
  • ****
  • Posts: 340
Reply #1 on: Jul 16, 2018
Answer to Question 1

ANS: A
Because steroid action involves modification of cell transcription, full antiinflammatory effects require hours to days. It is important for patients to understand that inhalation of an aerosolized steroid will not provide immediate relief as with an adrenergic bronchodilator. However, daily compliance with the inhaled medication is essential to controlling the inflammation of asthma.

Answer to Question 2

ANS: A
Ciclesonide, a prodrug, is given as an inactive compound and is converted to an active metabo-lite, desisobutyryl-ciclesonide (des-CIC), by intracellular enzymes.


jazziefee

  • Member
  • Posts: 505
Reply 2 on: Jul 16, 2018
Gracias!

cam1229

  • Member
  • Posts: 329
Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

« previous next »
 

Did you know?

The strongest synthetic topical retinoid drug available, tazarotene, is used to treat sun-damaged skin, acne, and psoriasis.

Did you know?

When intravenous medications are involved in adverse drug events, their harmful effects may occur more rapidly, and be more severe than errors with oral medications. This is due to the direct administration into the bloodstream.

Did you know?

The Centers for Disease Control and Prevention (CDC) was originally known as the Communicable Disease Center, which was formed to fight malaria. It was originally headquartered in Atlanta, Georgia, since the Southern states faced the worst threat from malaria.

Did you know?

The use of salicylates dates back 2,500 years to Hippocrates’s recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.

Did you know?

Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.

Mechanism of ERK activation and cell proliferation Mechanism of ERK activation and cell proliferation
Many European Americans are involved in ethnic work, attempting to maintain an identity more precise ... Many European Americans are involved in ethnic work, attempting to maintain an identity more precise ...
Work and Gender: Women at Work in India Work and Gender: Women at Work in India
Work and Gender: Women at Work in India Work and Gender: Women at Work in India
Role of Ras protein in a central growth factor activation pathway Role of Ras protein in a central growth factor activation pathway
Complement Activation and Results Complement Activation and Results
Video: Types of Shock (Part 2 of 2)

For a complete list of videos, visit our video library