The client receives tamoxifen (Nolvadex) for treatment of breast ...

[jrubin]

The client receives tamoxifen (Nolvadex) for treatment of breast cancer. She asks the nurse why the medicine works. What is the best response by the nurse?
 
  1. Tamoxifen (Nolvadex) works by inhibiting the metabolism of breast cancer cells..
   2. Tamoxifen (Nolvadex) works by blocking estrogen receptors on breast tissue..
   3. Tamoxifen (Nolvadex) works by inhibiting the cellular mitosis of breast cancer..
   4. Tamoxifen (Nolvadex) works by binding to the DNA of breast cancer cells..

Question 2

The client with cirrhosis has had a liver transplant and has returned to the unit following surgery. Which of the following is a postoperative priority outcome for this client?
 
  1. Normal pupil reaction
   2. Ability to move the legs
   3. Moist membranes of the mouth
   4. Normal body temperature

[meryzewe]

Answer to Question 1

2. Tamoxifen (Nolvadex) works by blocking estrogen receptors on breast tissue..

Rationale:
Breast cancer is dependent on estrogen for growth. Tamoxifen (Nolvadex) acts by blocking estrogen receptors; the tumor is deprived of estrogen. Tamoxifen (Nolvadex) does not inhibit the metabolism of breast cancer cells. Tamoxifen (Nolvadex) does not inhibit the cellular mitosis of breast cancer. Tamoxifen (Nolvadex) does not bind to the DNA of breast cancer cells.

Answer to Question 2

4. Normal body temperature

Rationale:
The postoperative liver transplant client often is hypothermic following surgery. Careful monitoring and rewarming techniques are a priority of care. Normal pupil reaction, leg movement, and moist mouth membranes are all normal findings for any postoperative client.