A health care provider is evaluating the results of hematologic ...

[bucstennis@aim.com]

A health care provider is evaluating the results of hematologic studies for a patient with cancer receiving busulfan (Myleran). Which of the following laboratory results would indicate that the patient is tolerating the drug?
 
  a. Absolute neutrophil count (ANC) of 4500/mm3
  b. Platelet count of 40,000/mm3
  c. Blood urea nitrogen (BUN) of 18 mg/dL
  d. Hematocrit of 28 mg/dL

Question 2

Which of the following drugs are considered to be antitumor antibiotics? Select all that apply.
 
  a. Bleomycin
  b. Dactinomycin
  c. Daunorubicin
  d. L-Asparaginase
  e. Idarubicin
  f. Mitotane (Lysodren)

[rleezy04]

Answer to Question 1

ANS: A
Alkylating drugs such as busulfan cause bone marrow suppression; therefore platelet counts less than 50,000/mm3 and hemoglobin values 11 mg/dL necessitate attention and will likely cause antineoplastic therapy to be withheld. A normal leukocyte count is 4000 to 10,000 cells/mm3. A patient is neutropenic if his or her ANC is 1000 cells/mm3. The frequency of infection increases as the ANC falls below 500 cells/mm3 as well as the longer the patient remains neutropenic.

Answer to Question 2

ANS: A, B, C, E
Bleomycin, dactinomycin, daunorubicin, and idarubicin are all considered antitumor antibiotics. L-Asparaginase and mitotane are both considered to be miscellaneous agents.

[bucstennis@aim.com]

TY

[rleezy04]

You're welcome