Which of the following is the mechanism by which the selective ...

[berenicecastro]

Which of the following is the mechanism by which the selective serotonin reuptake inhibitor (SSRI) antidepressant drugs appear to work?
 
  a. Blocking reuptake of gamma-aminobutyric acid (GABA) and substance P
  b. Blocking reuptake of serotonin and norepinephrine
  c. Enhancing reuptake of serotonin and norepinephrine
  d. Enhancing reuptake of GABA and substance P

Question 2

The health care provider teaches a patient beginning tricyclic antidepressant drug therapy about measures to minimize the most serious common adverse drug effects. Which of the following adverse reactions is considered the most serious?
 
  a. Orthostatic hypotension
  b. Dry mouth
  c. Blurred vision
  d. Urinary retention

[SVictor]

Answer to Question 1

ANS: B
Antidepressant drugs appear to work by blocking presynaptic reuptake of serotonin and norepi-nephrine.

Answer to Question 2

ANS: A
Orthostatic hypotension is the most serious of the common adverse effects of tricyclic antide-pressant drug therapy and is due, in part, to blockade of alpha-1 receptors on blood vessels.

[berenicecastro]

Excellent

[kilada]

Gracias!