A man takes a dose of sildenafil with grapefruit juice. What is the most likely adverse reaction?
1. Priapism
2. Hypertensive episode
3. Pallor and chills
4. Constipation
Question 2
An adult male has taken medication for the management of hypertension for 3 years. He says to a nurse, I'm not going to take these drugs anymore because they're interfering with my sex life. Select the nurse's best response.
1. It's unfortunate that these drugs can cause erectile dysfunction, but managing your blood pressure is more important than your sexual performance.
2. I understand how discouraging it must be to live with this side effect, but you could have a stroke if you don't take your blood pressure drugs.
3. Let's discuss this effect with your health care provider. There are drugs available to manage this side effect.
4. I'm glad you told me about your experience with this side effect. Sexual performance can be a difficult subject to discuss.
The steps of an enzyme-catalyzed reaction
Withdrawing Medication from Single-Dose or Multiple-Dose Vials
A typical reaction in which NAD+ acts as an oxidizing agent
First reaction requires thiamine pyrophosphate as a coenzyme
Mechanism for the reaction catalyzed by thymidylate synthase
Witting Reaction