The client receives tamoxifen for treatment of breast cancer. She ...

[nautica902]

The client receives tamoxifen for treatment of breast cancer. She asks the nurse why the medicine works. What is the best response by the nurse?
 
  1. Tamoxifen works by inhibiting the metabolism of breast cancer cells.
  2. Tamoxifen works by inhibiting the cellular mitosis of breast cancer.
  3. Tamoxifen works by blocking estrogen receptors on breast tissue.
  4. Tamoxifen works by binding to the DNA of breast cancer cells.

Question 2

Which statement is true regarding hormone antagonists?
 
  1. They are cytotoxic.
  2. They enhance substances essential for hormone growth.
  3. They produce similar debilitating adverse effects that other antineoplastics produce.
  4. They can produce debilitating adverse effects at high doses for prolonged periods.

[ciecieme]

Answer to Question 1

Correct Answer: 3
Rationale 1: Tamoxifen does not inhibit the metabolism of breast cancer cells.
Rationale 2: Tamoxifen does not inhibit the cellular mitosis of breast cancer.
Rationale 3: Tamoxifen acts by blocking estrogen receptors.
Rationale 4: Tamoxifen does not bind to the DNA of breast cancer cells.
Global Rationale: Tamoxifen works by blocking estrogen receptors on breast tissue. It does not inhibit the metabolism, inhibit cellular mitosis or bind to the DNA of breast cancer cells.

Answer to Question 2

Correct Answer: 4
Rationale 1: They are not cytotoxic.
Rationale 2: They block substances essential for hormone growth.
Rationale 3: They produce few debilitating adverse effects that other antineoplastics produce.
Rationale 4: This classification of medications can produce debilitating adverse effects when given at high doses for prolonged periods of time.
Global Rationale: In general, the hormones and hormone antagonists act by blocking the substances essential for tumor growth. Because these drugs are not cytotoxic, they produce few of the life-threatening toxic effects of antineoplastics from other classes. They can, however, produce significant adverse effects when given at high doses for prolonged periods.

[nautica902]

Thank you!

[ciecieme]

Always glad to help...